Hoffmann-La Roche
Scottsdale, Arizona
This company trades under its own ticker, so it sits outside Biodatica’s pre-ticker window. The record stays here because its filings are real, but the feed leaves listed companies out unless you ask for them.
What changed
Phase II trial registered: A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A
5d agoTrial registeredJul 14, 2026Source filing (opens the source filing in a new tab)
Momentum
Momentum 100 out of 100, unchanged since the last recompute.
Accelerating: several high-weight events landed recently.
Runway (estimate)
No disclosed raise on file, so there is nothing to model from.
Stage
Filed/Approved
The furthest-along thing in the public record. Not a projection.
Runway is an estimate: the last disclosed raise (SEC Form D) minus a modeled burn rate for the company’s stage and therapeutic area. It is not a disclosure, and companies routinely raise non-dilutive money we can’t see. How this is calculated.
Grant to raise
Every record Biodatica has resolved onto this company, newest first, each linked to the filing it came from. Where a source publishes no stable deep link for a record, the identifier is shown so you can look it up yourself.
- Trial
PHASE1 registered
Jul 31, 2026Metastatic Colorectal Cancer · NOT_YET_RECRUITING · sponsor: Hoffmann-La Roche · A Study to Investigate CEA-PRIT 2.0 in Participants With Metastatic Colorectal Cancer (mCRC)
ClinicalTrials.gov · NCT07416552 (opens the source filing in a new tab)
- Trial
PHASE1/PHASE2 registered
Jul 14, 2026Hemophilia A · RECRUITING · sponsor: Hoffmann-La Roche · A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A
ClinicalTrials.gov · NCT07226206 (opens the source filing in a new tab)
- Trial
PHASE1 registered
Jul 2, 2026Healthy Participants · RECRUITING · sponsor: Hoffmann-La Roche · A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Enicepatide in Generally Healthy Adult Chinese Participants
ClinicalTrials.gov · NCT07626515 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Mar 16, 2026Obesity or Overweight · RECRUITING · sponsor: Hoffmann-La Roche · A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
ClinicalTrials.gov · NCT07351045 (opens the source filing in a new tab)
- Trial
PHASE2 registered
Mar 10, 2026Progressive Multiple Sclerosis · RECRUITING · sponsor: Hoffmann-La Roche · A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)
ClinicalTrials.gov · NCT07282574 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Nov 12, 2025Alzheimers Disease · RECRUITING · sponsor: Hoffmann-La Roche · A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
ClinicalTrials.gov · NCT07170150 (opens the source filing in a new tab)
- Trial
PHASE2 registered
Aug 19, 2025Type 2 Diabetes Mellitus · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes
ClinicalTrials.gov · NCT07112872 (opens the source filing in a new tab)
- Trial
PHASE1 registered
Feb 13, 2025Healthy Participants · COMPLETED · sponsor: Hoffmann-La Roche · A Study Investigating the Effect of Different Approved Medications on How the Body Processes the Study Compound RO7795081
ClinicalTrials.gov · NCT06809608 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Nov 15, 2023Thyroid Eye Disease · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease
ClinicalTrials.gov · NCT06106828 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Sep 18, 2023Large B-Cell Lymphoma · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · An Open-Label Study Comparing Glofitamab and Polatuzumab Vedotin + Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone Versus Pola-R-CHP in Previously Untreated Patients With Large B-Cell Lymphoma
ClinicalTrials.gov · NCT06047080 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Jun 28, 2023Chronic Obstructive Pulmonary Disease · RECRUITING · sponsor: Hoffmann-La Roche · A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
ClinicalTrials.gov · NCT05878769 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Mar 23, 2023Uveitic Macular Edema · COMPLETED · sponsor: Hoffmann-La Roche · Vamikibart in Participants With Uveitic Macular Edema
ClinicalTrials.gov · NCT05642325 (opens the source filing in a new tab)
- Trial
PHASE2/PHASE3 registered
Feb 27, 2023Cancer · TERMINATED · sponsor: Hoffmann-La Roche · Clinical Impact and Utility of Digital Health Solutions in Participants Receiving Systemic Treatment in Clinical Practice
ClinicalTrials.gov · NCT05694013 (opens the source filing in a new tab)
- Trial
PHASE1/PHASE2 registered
Nov 16, 2022Mature B-Cell Non-Hodgkin Lymphoma · RECRUITING · sponsor: Hoffmann-La Roche · A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
ClinicalTrials.gov · NCT05533775 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Sep 27, 2022NMDAR Autoimmune Encephalitis, LGI1 Autoimmune Encephalitis · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methyl-D-aspartic Acid Receptor (NMDAR) or Anti-leucine-rich Glioma-inactivated 1 (LGI1) Encephalitis
ClinicalTrials.gov · NCT05503264 (opens the source filing in a new tab)
- Trial
PHASE4 registered
Jun 20, 2022Severe Hemophilia A, Moderate Hemophilia A · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis
ClinicalTrials.gov · NCT05181618 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Jun 14, 2022Non-Small Cell Lung Cancer · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study of Atezolizumab in High PD-L1 Expression, Chemotherapy-Naïve Patients With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer
ClinicalTrials.gov · NCT05047250 (opens the source filing in a new tab)
- Trial
PHASE2/PHASE3 registered
Jun 2, 2022Spinal Muscular Atrophy (SMA) · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy
ClinicalTrials.gov · NCT05115110 (opens the source filing in a new tab)
- Trial
PHASE1 registered
Jan 11, 2022Systemic Lupus Erythematosus · COMPLETED · sponsor: Hoffmann-La Roche · A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered Mosunetuzumab to Participants With Systemic Lupus Erythematosus
ClinicalTrials.gov · NCT05155345 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Oct 27, 2021Relapsed or Refractory Follicular Lymphoma · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study Evaluating the Efficacy and Safety of Mosunetuzumab in Combination With Lenalidomide in Comparison to Rituximab in Combination With Lenalidomide With a US Extension of Mosunetuzumab in Combination With Lenalidomide in Participants With Follicular Lymphoma
ClinicalTrials.gov · NCT04712097 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Sep 30, 2021Carcinoma, Non-Small-Cell Lung · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases
ClinicalTrials.gov · NCT04603807 (opens the source filing in a new tab)
- Trial
PHASE1/PHASE2 registered
Sep 14, 2021ALK Fusion-positive Solid or CNS Tumors · RECRUITING · sponsor: Hoffmann-La Roche · A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors
ClinicalTrials.gov · NCT04774718 (opens the source filing in a new tab)
- Trial
Study registered
May 10, 2021NSCLC · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · An Observational Study to Evaluate the Real-World Clinical Management and Outcomes of ALK-Positive Advanced NSCLC Participants Treated With Alectinib
ClinicalTrials.gov · NCT04764188 (opens the source filing in a new tab)
- Trial
PHASE3 registered
May 4, 2021Carcinoma, Hepatocellular · TERMINATED · sponsor: Hoffmann-La Roche · A Study of Atezolizumab in Combination With Bevacizumab in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy
ClinicalTrials.gov · NCT04732286 (opens the source filing in a new tab)
- Trial
PHASE3 registered
May 4, 2021Breast Cancer · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy
ClinicalTrials.gov · NCT04873362 (opens the source filing in a new tab)
- Trial
PHASE2 registered
Mar 31, 2021Autism Spectrum Disorder (ASD) · COMPLETED · sponsor: Hoffmann-La Roche · A 12-Week Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of RO7017773 in Participants Aged 15-45 Years With Autism Spectrum Disorder (ASD)
ClinicalTrials.gov · NCT04299464 (opens the source filing in a new tab)
- Trial
PHASE1/PHASE2 registered
Mar 15, 2021Alzheimers Disease · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease
ClinicalTrials.gov · NCT04639050 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Nov 26, 2020Multiple Sclerosis · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)
ClinicalTrials.gov · NCT04544436 (opens the source filing in a new tab)
- Trial
PHASE2 registered
Nov 25, 2020Diabetic Macular Edema · COMPLETED · sponsor: Hoffmann-La Roche · A Study to Investigate Aqueous Humor and Multimodal Imaging Biomarkers in Treatment-Naïve Participants With Diabetic Macular Edema Treated With Faricimab
ClinicalTrials.gov · NCT04597918 (opens the source filing in a new tab)
- Trial
PHASE1 registered
Nov 11, 2020Multiple Myeloma · COMPLETED · sponsor: Hoffmann-La Roche · A Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of Forimtamig in Participants With Relapsed or Refractory Multiple Myeloma (r/r MM)
ClinicalTrials.gov · NCT04557150 (opens the source filing in a new tab)
- Trial
Study registered
Aug 27, 2020Solid Tumours · COMPLETED · sponsor: Hoffmann-La Roche · A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test
ClinicalTrials.gov · NCT04529122 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Aug 25, 2020Carcinoma, Hepatocellular · COMPLETED · sponsor: Hoffmann-La Roche · A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista
ClinicalTrials.gov · NCT04487067 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Sep 30, 2019Diabetic Macular Edema · ACTIVE_NOT_RECRUITING · sponsor: Hoffmann-La Roche · A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DME
ClinicalTrials.gov · NCT04108156 (opens the source filing in a new tab)
- Trial
Study registered
Nov 12, 2018Multiple Sclerosis · COMPLETED · sponsor: Hoffmann-La Roche · Non-interventional Study of Ocrelizumab in Participants With Relapsing or Primary Progressive Multiple Sclerosis
ClinicalTrials.gov · NCT03593590 (opens the source filing in a new tab)
- Trial
PHASE3 registered
Nov 16, 2017Diffuse Large B-Cell Lymphoma · COMPLETED · sponsor: Hoffmann-La Roche · A Study Comparing the Efficacy and Safety of Polatuzumab Vedotin With Rituximab-Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Diffuse Large B-Cell Lymphoma
ClinicalTrials.gov · NCT03274492 (opens the source filing in a new tab)
- Trial
PHASE1/PHASE2 registered
Oct 13, 2017Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma · COMPLETED · sponsor: Hoffmann-La Roche · A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)
ClinicalTrials.gov · NCT03281369 (opens the source filing in a new tab)
Biodatica publishes impersonal research shown identically to every subscriber. This dossier is informational only, it is not investment advice, and the momentum and runway figures are estimates derived from public filings. The underlying records are U.S. government works. Disclosures · Data sources