INSTITUTE FOR SYSTEMS BIOLOGY

SEATTLE, WA

OncologyGrant-only

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What changed

NIH R01 · $0.5M · Immunometabolic regulation of inflammaging by nerve-associated macrophages

6w agoNew grantJun 3, 2026Source filing (opens the source filing in a new tab)

Momentum

82no change

Accelerating: several high-weight events landed recently.

Runway (estimate)

—unknown

No disclosed raise on file, so there is nothing to model from.

Stage

Grant-only

The furthest-along thing in the public record. Not a projection.

Runway is an estimate: the last disclosed raise (SEC Form D) minus a modeled burn rate for the company’s stage and therapeutic area. It is not a disclosure, and companies routinely raise non-dilutive money we can’t see. How this is calculated.

Grant to raise

Every record Biodatica has resolved onto this company, newest first, each linked to the filing it came from. Where a source publishes no stable deep link for a record, the identifier is shown so you can look it up yourself.

Grant
R01 · $544k · non-dilutive
Jun 1, 2026
YALE UNIVERSITY · PI DIXIT, VISHWA DEEP · NIA · award ends May 31, 2031 · Immunometabolic regulation of inflammaging by nerve-associated macrophages
NIH RePORTER · NIH RePORTER 11341489 (opens the source filing in a new tab)
Grant
R01 · $701k · non-dilutive
Feb 1, 2026
UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHI, LINGYAN · NIA · award ends Jan 31, 2031 · Lympnoids tissue senescence and multimodal imaging using REDCAT
NIH RePORTER · NIH RePORTER 11297324 (opens the source filing in a new tab)
Grant
U01 · $4.1M · non-dilutive
Sep 1, 2024
YALE UNIVERSITY · PI FAN, RONG · NCI · award ends Aug 31, 2029 · Center for Human Lymphoma Spatiotemporal Atlas (HuLymSTA)
NIH RePORTER · NIH RePORTER 11177041 (opens the source filing in a new tab)
Grant
U54 · $290k · non-dilutive
Sep 22, 2022
INSTITUTE FOR SYSTEMS BIOLOGY · PI FAN, RONG · NCI · award ends Aug 31, 2027 · Core 2: Tissue Imaging and Profiling Core
NIH RePORTER · NIH RePORTER 11191440 (opens the source filing in a new tab)
Grant
R01 · $442k · non-dilutive
Jul 1, 2022
YALE UNIVERSITY · PI DIXIT, VISHWA DEEP · NIA · award ends Mar 31, 2027 · Caloric restriction-driven immunometabolic checkpoints of inflammation
NIH RePORTER · NIH RePORTER 11304067 (opens the source filing in a new tab)
Grant
R01 · $480k · non-dilutive
Jun 15, 2022
YALE UNIVERSITY · PI DIXIT, VISHWA DEEP · NIA · award ends Mar 31, 2027 · Immunometabolic regulation of bone inflammaging
NIH RePORTER · NIH RePORTER 11301887 (opens the source filing in a new tab)
Grant
R01 · $585k · non-dilutive
Feb 3, 2022
YALE UNIVERSITY · PI BINDRA, RANJIT · NCI · award ends Jan 31, 2027 · Targeting Defective DNA Damage Response Pathways in IDH1/2-mutant AML
NIH RePORTER · NIH RePORTER 11258988 (opens the source filing in a new tab)
Grant
P01 · $2.5M · non-dilutive
Sep 15, 2016
YALE UNIVERSITY · PI DIXIT, VISHWA DEEP · NIA · award ends May 31, 2027 · Competing Renewal P01
NIH RePORTER · NIH RePORTER 11377500 (opens the source filing in a new tab)
Grant
P01 · $266k · non-dilutive
Sep 15, 2016
YALE UNIVERSITY · PI DIXIT, VISHWA DEEP · NIA · award ends May 31, 2027 · Admin-Core
NIH RePORTER · NIH RePORTER 11377502 (opens the source filing in a new tab)
Grant
P01 · $551k · non-dilutive
Sep 15, 2016
YALE UNIVERSITY · PI DIXIT, VISHWA DEEP · NIA · award ends May 31, 2027 · Project 1 - Dixit
NIH RePORTER · NIH RePORTER 11377505 (opens the source filing in a new tab)
Grant
P01 · $541k · non-dilutive
Sep 15, 2016
YALE UNIVERSITY · PI DIXIT, VISHWA DEEP · NIA · award ends May 31, 2027 · Healthspan Core
NIH RePORTER · NIH RePORTER 11377503 (opens the source filing in a new tab)

How this crosswalk was built

Confidence 58%Edges merged automatically, not yet reviewed by a human

Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator
Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator
Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator
Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator
Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator
Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator
Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator
Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator
Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator
Shared principal investigator or founder links the grant record at 0.75grant to an academic institution linked by a shared principal investigator

Links score at or above 0.86 to merge automatically. Anything below that and above the review line goes to a human queue. Resolution is a judgment, and it can be wrong. How resolution works.

Event stream

Every scored event, newest first. This is what momentum is computed from.

NIH R01 · $0.5M · Immunometabolic regulation of inflammaging by nerve-associated macrophages
6w agoNew grantSource (opens the source filing in a new tab)
NIH P01 · $2.5M · Competing Renewal P01
2mo agoGrant renewalSource (opens the source filing in a new tab)
NIH P01 · $0.3M · Admin-Core
2mo agoGrant renewalSource (opens the source filing in a new tab)
NIH P01 · $0.6M · Project 1 - Dixit
2mo agoGrant renewalSource (opens the source filing in a new tab)
NIH P01 · $0.5M · Healthspan Core
2mo agoGrant renewalSource (opens the source filing in a new tab)
NIH R01 · $0.4M · Caloric restriction-driven immunometabolic checkpoints of inflammation
3mo agoGrant renewalSource (opens the source filing in a new tab)
NIH R01 · $0.5M · Immunometabolic regulation of bone inflammaging
4mo agoGrant renewalSource (opens the source filing in a new tab)
NIH R01 · $0.7M · Lympnoids tissue senescence and multimodal imaging using REDCAT
5mo agoNew grantSource (opens the source filing in a new tab)
NIH R01 · $0.6M · Targeting Defective DNA Damage Response Pathways in IDH1/2-mutant AML
5mo agoGrant renewalSource (opens the source filing in a new tab)
NIH U01 · $4.1M · Center for Human Lymphoma Spatiotemporal Atlas (HuLymSTA)
9mo agoGrant renewalSource (opens the source filing in a new tab)
NIH U54 · $0.3M · Core 2: Tissue Imaging and Profiling Core
10mo agoGrant renewalSource (opens the source filing in a new tab)

Last disclosed raise

No Form D is on file, so there is no raise to model a runway from. That is why the runway reads “—” rather than a number. It does not mean the company has no money: grants, revenue and notes below the Form D threshold are all invisible here.

Something wrong on this page? The crosswalk is a judgment and we would rather hear it. Report a bad link.

Biodatica publishes impersonal research shown identically to every subscriber. This dossier is informational only, it is not investment advice, and the momentum and runway figures are estimates derived from public filings. The underlying records are U.S. government works. Disclosures · Data sources

Grant to raise

R01 · $544k · non-dilutive

R01 · $701k · non-dilutive

U01 · $4.1M · non-dilutive

U54 · $290k · non-dilutive

R01 · $442k · non-dilutive

R01 · $480k · non-dilutive

R01 · $585k · non-dilutive

P01 · $2.5M · non-dilutive

P01 · $266k · non-dilutive

P01 · $551k · non-dilutive

P01 · $541k · non-dilutive